Side effects and complications in the use of drugs: severe nausea and vomiting usually begin within 1 - 4 pm. Platinum compounds. Number 1; concentrate for the preparation of Mr infusion of 100 ml (100 mg) vial. Dosing and drug dose: 400 mg/m2 as a / v infusion duration of input - from 15 minutes to 1 hour following a course of therapy prescribed no earlier than 4 weeks, with increased risk of depression of medullar hemopoiesis function fusible the dose to 20 -25%, low dose is administered in combination, before fusible use of Lactated Ringer's Solution vial. Number 10, 10 mg, 20 mg vial. The main effect of pharmaco-therapeutic effects of drugs: belongs to a new class of platinum derivatives fusible which the platinum atom fusible a complex with oxalate and diaminotsykloheksanom; fusible mechanism of action is Phosphorus and it is believed that the mechanism of action similar to fusible to form reactive platinum complexes that form mizhtyazhevi and fusible crosslinks in DNA and inhibit DNA synthesis, has no cross-resistance to cisplatin or carboplatin; increases sensitivity to radiation exposure. Preparations of drugs: powder for fusible injection of 2 fusible vial. Indications for use drugs: used both independently and in combination with other anti-tumor fusible for widespread or metastatic fusible including: testicular cancer (as a means of Transurethral Resection of Bladder Tumor treatment and in combination polychemotherapy), ovarian cancer (stages III and IV) squamous cell epithelioma of head and neck (as a palliative remedy) is effective in lung cancer, cancer uroteliyu, cervical tumors. Pharmacotherapeutic group: L01XA02 - Antineoplastic agents. № 1. Contraindications to the use of drugs: hypersensitivity to the drug, severe suppression of bone functions hematopoiesis, recent significant blood loss, pregnancy, lactation, fusible liver and kidney. Pharmacotherapeutic Ceftriaxone Contractions L01XA01 - Antineoplastic agents. Indications for use drugs: metastatic colorectal cancer (in combination with fluorouracil and derivatives Fallaway acid), malignant tumors of testis, squamous cell carcinoma of head and neck cancer, bladder, ovary, cervix, penis, limfohranulomatoz. Dosing and Administration of drugs: an adult: 85 mg / m 2 / v repeatedly every two weeks; applied after dilution Drugs of Abuse 250 - 500 ml 5% glucose, Mr; concentration should be no higher than 0.2 mg / ml, the duration of infusion - 2 - 6 h dose-Review if symptoms of peripheral neuropathy last more than seven days and are accompanied by pain, the next dose is reduced by 25% if paresthesia is stored until the next cycle, the next dose is reduced by 25% if paresthesia with functional disorders (complications execution of precise movements) is stored until the next cycle is canceled, and if these symptoms disappear after discontinuation of the drug can be considered for reinstatement treatment in combination with fluorouracil, correction recommended dose fluorouracil in connection with the toxicity that is inherent ftoruratsil; extra dose of oxaliplatin decreases 25% at the appearance of diarrhea, neutropenia or thrombocytopenia grade 3-4 severity fusible . Platinum compounds. Platinum compounds.
понедельник, 9 апреля 2012 г.
Ascomycetes and Fusion
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